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Jian Yang Selected Research

Osteosarcoma (Osteogenic Sarcoma)

1/2024Prolyl isomerase Pin1 promotes autophagy and cancer cell viability through activating FoxO3 signalling.
12/2021Human umbilical vein endothelial cells derived-exosomes promote osteosarcoma cell stemness by activating Notch signaling pathway.
1/2021A Novel Six Metastasis-Related Prognostic Gene Signature for Patients With Osteosarcoma.
1/2020Gukang Capsule Promotes Fracture Healing by Activating BMP/SMAD and Wnt/β-Catenin Signaling Pathways.
1/2019Notch pathway inhibition using DAPT, a γ-secretase inhibitor (GSI), enhances the antitumor effect of cisplatin in resistant osteosarcoma.
1/2018Cinobufagin Induces Apoptosis in Osteosarcoma Cells Via the Mitochondria-Mediated Apoptotic Pathway.
10/2017The synergistic antitumor effect of cinobufagin and cisplatin in human osteosarcoma cell line in vitro and in vivo.
10/2017Baicalein inhibits progression of osteosarcoma cells through inactivation of the Wnt/β-catenin signaling pathway.
4/2017Notch signaling is important for epithelial-mesenchymal transition induced by low concentrations of doxorubicin in osteosarcoma cell lines.
1/2017Long noncoding RNA NBAT1 negatively modulates growth and metastasis of osteosarcoma cells through suppression of miR-21.
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Jian Yang Research Topics

Disease

301Neoplasms (Cancer)
05/2024 - 03/2003
95Inflammation (Inflammations)
05/2024 - 05/2007
58Infections
04/2024 - 09/2003
55Hepatocellular Carcinoma (Hepatoma)
01/2024 - 12/2008
46Hypertension (High Blood Pressure)
03/2024 - 12/2003
45Neoplasm Metastasis (Metastasis)
03/2024 - 02/2011
43Fibrosis (Cirrhosis)
05/2024 - 09/2007
41Reperfusion Injury
05/2024 - 01/2008
38Cardiovascular Diseases (Cardiovascular Disease)
03/2024 - 06/2007
38Myocardial Ischemia (Ischemic Heart Diseases)
01/2023 - 06/2007
37Myocardial Infarction
05/2024 - 08/2002
34Wounds and Injuries (Trauma)
03/2024 - 01/2007
30Alzheimer Disease (Alzheimer's Disease)
03/2024 - 12/2014
30Atherosclerosis
01/2024 - 08/2002
29Pain (Aches)
04/2024 - 01/2011
26Carcinogenesis
03/2024 - 07/2006
26Breast Neoplasms (Breast Cancer)
12/2023 - 07/2006
23Virus Diseases (Viral Diseases)
04/2024 - 06/2011
23Ischemia
03/2024 - 01/2007
22Pancreatic Neoplasms (Pancreatic Cancer)
08/2023 - 05/2012
21Hypoxia (Hypoxemia)
03/2024 - 07/2010
20Heart Failure
05/2024 - 01/2013
20COVID-19
11/2023 - 01/2020
18Stomach Neoplasms (Stomach Cancer)
04/2024 - 11/2009
18Stroke (Strokes)
01/2024 - 12/2006
17Infarction (Infarctions)
04/2024 - 10/2009
17Hemorrhage
03/2024 - 11/2012
17Necrosis
03/2023 - 12/2007
16Lung Neoplasms (Lung Cancer)
02/2024 - 01/2004
16Osteosarcoma (Osteogenic Sarcoma)
01/2024 - 01/2014
16Obesity
01/2023 - 12/2012
15Colorectal Neoplasms (Colorectal Cancer)
05/2024 - 06/2008
15Major Depressive Disorder (Major Depressive Disorders)
03/2024 - 01/2019
15Thrombosis (Thrombus)
01/2024 - 04/2008
14Body Weight (Weight, Body)
11/2023 - 12/2006
14Neuralgia (Stump Neuralgia)
01/2023 - 01/2011
14Diabetes Mellitus
01/2022 - 09/2004
13Parkinson Disease (Parkinson's Disease)
01/2024 - 03/2006
13Cardiomegaly (Heart Hypertrophy)
01/2024 - 06/2007
13Insulin Resistance
12/2023 - 05/2012
13Rheumatoid Arthritis
07/2023 - 05/2007
13Carcinoma (Carcinomatosis)
01/2023 - 11/2006
12Adenocarcinoma of Lung
03/2024 - 07/2014
12Adenocarcinoma
01/2024 - 01/2007
12Glioma (Gliomas)
12/2023 - 09/2010
11Atrial Fibrillation
04/2024 - 12/2014
11Hyperglycemia
03/2024 - 11/2004
11Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
02/2024 - 06/2012
11Coronary Artery Disease (Coronary Atherosclerosis)
01/2023 - 10/2014
11Prostatic Neoplasms (Prostate Cancer)
01/2023 - 09/2008
11Hyperplasia
01/2023 - 12/2006
11Schizophrenia (Dementia Praecox)
03/2022 - 09/2013
10Osteoporosis
05/2024 - 01/2003
10Heart Diseases (Heart Disease)
05/2024 - 06/2007
10Non-alcoholic Fatty Liver Disease
01/2024 - 05/2013
10Glioblastoma (Glioblastoma Multiforme)
11/2023 - 09/2010
10Neurodegenerative Diseases (Neurodegenerative Disease)
09/2023 - 09/2009

Drug/Important Bio-Agent (IBA)

119Proteins (Proteins, Gene)FDA Link
05/2024 - 09/2007
75Biomarkers (Surrogate Marker)IBA
05/2024 - 08/2006
41MicroRNAs (MicroRNA)IBA
09/2022 - 06/2007
40Messenger RNA (mRNA)IBA
12/2023 - 01/2008
35CytokinesIBA
06/2024 - 09/2007
31LipidsIBA
05/2024 - 12/2006
29Glucose (Dextrose)FDA LinkGeneric
05/2024 - 11/2004
28EnzymesIBA
05/2024 - 10/2009
27Therapeutic UsesIBA
06/2024 - 07/2008
26Long Noncoding RNAIBA
02/2024 - 01/2016
24Peptides (Polypeptides)IBA
11/2023 - 10/2007
22Reactive Oxygen Species (Oxygen Radicals)IBA
06/2024 - 12/2003
20RNA (Ribonucleic Acid)IBA
01/2024 - 02/2013
19DNA (Deoxyribonucleic Acid)IBA
11/2023 - 01/2004
18CollagenIBA
02/2024 - 05/2007
16koumineIBA
07/2023 - 05/2012
15Doxorubicin (Adriamycin)FDA LinkGeneric
05/2024 - 01/2014
15Interleukin-6 (Interleukin 6)IBA
03/2024 - 09/2007
14AlkaloidsIBA
02/2024 - 05/2007
14Anti-Bacterial Agents (Antibiotics)IBA
01/2024 - 09/2003
14AntigensIBA
03/2023 - 01/2007
14Small Interfering RNA (siRNA)IBA
12/2019 - 07/2009
13Transcription Factors (Transcription Factor)IBA
04/2024 - 02/2015
13AntioxidantsIBA
03/2024 - 01/2013
12CholesterolIBA
02/2024 - 08/2002
12LigandsIBA
06/2023 - 01/2011
12L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
02/2023 - 01/2014
12Analgesics (Analgesic Drugs)IBA
01/2022 - 01/2011
10AlbuminsIBA
01/2024 - 05/2004
10CalciumIBA
01/2024 - 01/2003
10Protein Kinases (Protein Kinase)IBA
12/2023 - 03/2013
10Phosphotransferases (Kinase)IBA
10/2023 - 11/2005

Therapy/Procedure

158Therapeutics
05/2024 - 07/2006
37Drug Therapy (Chemotherapy)
11/2023 - 11/2005
25Immunotherapy
02/2024 - 01/2007
23Hepatectomy
01/2024 - 04/2009
17Stents
02/2024 - 12/2006
16Chinese Traditional Medicine (Traditional Chinese Medicine)
02/2024 - 02/2014
12Radiotherapy
04/2024 - 01/2017
12Length of Stay
01/2024 - 12/2006
11Precision Medicine
03/2024 - 04/2013
11Aftercare (After-Treatment)
03/2023 - 11/2006
10Transplantation
01/2024 - 06/2007